Functions and emerging applications of bacteriocins | 食品添加物合法業者資訊網

由MLChikindas著作·2018·被引用324次—Bacteriocins,definedasribosomallysynthesizedantimicrobialpeptides,havetraditionallybeenusedasfoodpreservatives,eitheraddedor ...

Bacteriocins, defined as ribosomally synthesized antimicrobial peptides, have traditionally been used as food preservatives, either added or produced by starter cultures during fermentation. In-depth studies of a select few bacteriocins opened exiting new research fields and broadened the application of these antimicrobial peptides. The possibility of developing bacteriocins into next generation antibiotics, accompanied with the rapid development in genetics and nanotechnology, paves the way to even more fascinating applications such as novel carrier molecules (delivery systems) and the treatment of cancer. Also, some bacteriocins are found to regulate quorum sensing which suggests novel applications for this group of substances. While there is some interesting translational research on bacteriocins from Gramnegative bacteria, the majority of application-oriented studies are focused on bacteriocins from Grampositive microorganisms, mostly lactic acid bacteria. The a...