Macrolide effects on the prevention of COPD exacerbations | 食品添加物合法業者資訊網

由MYamaya著作·2012·被引用81次—TreatmentwithmacrolideantibioticshasbeenreportedtopreventCOPDexacerbationsandimprovepatientqualityoflifeandsymptoms,especiallyinthose ...

The number of senile patients with chronic obstructive pulmonary disease (COPD) has recently increased due to an increase in life expectancy, the habit of smoking and the inhalation of toxic particles. COPD exacerbations are caused by airway bacterial and viral infections, as well as the inhalation of oxidative substrates. COPD exacerbations are associated with the worsening of symptoms and quality of life, as well as an increased mortality rate.

Several drugs, including long-acting anti-cholinergic agents, long-acting β2-agonists and inhaled corticosteroids, have been developed to improve symptoms in COPD patients and to prevent COPD exacerbations. Treatment with macrolide antibiotics has been reported to prevent COPD exacerbations and improve patient quality of life and symptoms, especially in those patients who have frequen...