Aldol reaction | 食品添加物合法業者資訊網

Intramolecularaldolreactionisthecondensationreactionoftwoaldehydegroupsorketonegroupsinthesamemolecule.Five-orsix-memberedα,β-​unsaturated ...

Chemical reaction

The aldol reaction (aldol addition) is a reaction in organic chemistry that combines two carbonyl compounds (e.g. aldehydes or ketones) to form a new β-hydroxy carbonyl compound. Its simplest form might involve the nucleophilic addition of an enolized ketone to another:

These products are known as aldols, from the aldehyde + alcohol, a structural motif seen in many of the products. The use of aldehyde in the name comes from its history: aldehydes are more reactive than ketones, so that the reaction was discovered first with them.[2][3][4]

The aldol reaction is paradigmatic in organic chemistry and perhaps the most common means of forming carbon–carbon bonds in organic chemistry.[5][6][7] It lends its name to the family of aldol reactions and similar techniques analyze a whole family of carbonyl α-substitution reactions, as well as the diketone condensations. When the nucleophile and electrophile are different, the...