Bacteriocins: An Overview of Antimicrobial | 食品添加物合法業者資訊網

由DFBenítez-Chao著作·2021·被引用25次—Bacteriocinsareagroupofantimicrobialpeptidesproducedbybacteria,capableofcontrollingclinicallyrelevantsusceptibleanddrug- ...

According to the WHO, diseases caused by multidrug-resistant (MDR) pathogens are a serious worldwide public health problem (World Health Organization, 2019c[1]). The rapid spread of MDR pathogens have reduced the effectiveness of common antibiotics (Gupta and Datta, 2019[2]). Therefore, there is a particular need for the development of new antimicrobial agents, specifically those directed against MDR bacteria (Fair and Tor, 2014[3]). Bacteriocins represent the most important group of antimicrobial peptides with applications in human health (Marshall and Arenas, 2003[4]). The ability of bacteriocins to kill or inhibit relevant pathogenic bacteria (including MDR pathogens) in vitro has been well documented (Cui et al., 2012[5]; Gabrielsen et al., 2014[6]; Perez et al., 2014[7]; Newstead et al., 2020[8]). However, the use of animal models is an important part in the research toward the development of new therapeutic agents. There are many animal models used fo...