Table of Substrates | 食品添加物合法業者資訊網

2020年3月10日—TableofSubstrates,InhibitorsandInducers(including:CYP...Recommendtheuseof2structurallyunrelatedCYP3A4/5substratesfor ...

CYP Enzymes In vitro Clinical index drugs Examples of clinical substrates, inhibitors, and inducers Transporters In vitro Examples of clinical substrates, inhibitors and inducers

Table 1-1: Examples of in vitro marker reactions for CYP-mediated metabolism

Enzyme

Marker reaction

CYP1A2

7-ethoxyresorufin-O-deethylation, phenacetin O-deethylation

CYP2B6

...

Drug Metabolism | 食品添加物合法業者資訊網

Table of Substrates | 食品添加物合法業者資訊網

2020年3月10日 — Table of Substrates, Inhibitors and Inducers (including: CYP ... Recommend the use of 2 structurally unrelated CYP3A4/5 substrates for ... Read More

Cytochrome P450 3A inhibitors and inducers | 食品添加物合法業者資訊網

Classified as a weak inhibitor of CYP3A4 according to FDA system. ¶ Classified as a weak inducer of CYP3A4 according to FDA system. Read More

CYP3A4 | 食品添加物合法業者資訊網

Inhibition through fruit ingestion — ... is a potent inhibitor of CYP3A4, which can affect the ... Pomegranate juice has shown some inhibition in ... Read More

Common Medications Classified as Weak | 食品添加物合法業者資訊網

Strong inhibitors of CYP3A4 include: Clarithromycin, telithromycin, nefazodone, itraconazole, ketoconazole, atazanavir, darunavir, indinavir, lopinavir, ... Read More

Cytochrome P | 食品添加物合法業者資訊網

The Effect of Cytochrome P450 Metabolism on Drug ... | 食品添加物合法業者資訊網

由 T Lynch 著作 · 2007 · 被引用 1027 次 — Cytochrome P450 enzymes can be inhibited or induced by drugs, resulting in ... Ritonavir (Norvir), a protease inhibitor and potent CYP3A4 ... Read More

Effect of CYP3A4 Inhibitors and Inducers on Pharmacokinetics ... | 食品添加物合法業者資訊網

2021年10月19日 — Ketoconazole and rifampicin are recommended as the standard CYP3A4 competitive inhibitor and inducer for the potential clinical DDI study, ... Read More

相關資訊整理

Table of Substrates | 食品添加物合法業者資訊網

Drug Metabolism | 食品添加物合法業者資訊網

Table of Substrates | 食品添加物合法業者資訊網

Cytochrome P450 3A inhibitors and inducers | 食品添加物合法業者資訊網

CYP3A4 | 食品添加物合法業者資訊網

Common Medications Classified as Weak | 食品添加物合法業者資訊網

Cytochrome P | 食品添加物合法業者資訊網

The Effect of Cytochrome P450 Metabolism on Drug ... | 食品添加物合法業者資訊網

Effect of CYP3A4 Inhibitors and Inducers on Pharmacokinetics ... | 食品添加物合法業者資訊網

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