[Thiamine (vitamin B1) treatment in patients with alcohol ... | 食品添加物合法業者資訊網

由ADervaux著作·2017·被引用17次—Thiaminedeficiency(vitaminB1)iscommoninpatientswithalcoholdependence.Cognitiveimpairmentsmaybeanearlyconsequenceofthiaminedeficiency.

Thiamine deficiency (vitamin B1) is common in patients with alcohol dependence. Cognitive impairments may be an early consequence of thiamine deficiency. Wernickes encephalopathy is underdiagnosed and undertreated. In patients with established Wernickes encephalopathy, parenteral thiamine 200-500mg three times a day should be given for 3-5 days, followed by oral thiamine 250-1000mg/day. In patients with suspected Wernickes encephalopathy, parenteral thiamine 250-300mg should be given two times a day for 3-5 days, followed by oral thiamine 250-300mg/day. In patients at high risk of thiamine deficiency, parenteral thiamine 250-500mg/day should be given for 3-5 days, followed by oral thiamine 250-300mg/day. In patients at low risk (with uncomplicated alcohol dependence), oral thiamine 250-500mg/day should be given for 3-5 days, followed by oral thiamine 100-250mg/day.